34. Plasmodial resistance to chloroquine is due to(2.5分)

A、
A、Changeinreceptorstructure
B、
B、IncreaseintheactivityofDNArepairmechanisms
C、
C、Increasedsynthesisofdihydrofolatereductase
D、
D、Inductionofdrug-inactivatingenzymes#
E、Reducedaccumulationofthedruginthefoodvacuole
E、
E、Reducedaccumulationofthedruginthefoodvacuole